Indications and Usage

Clofarabine is FDA approved to treat children and young adults (1- 21 years old) with relapsed or refractory acute lymphoblastic leukemia after at least two prior regimens.

Side effects needing medical attention

Black, tarry stools; bleeding gums; blood in urine or stool; blurred vision; burning or stinging of skin; chest pain; chills; clay-colored stools; confusion; cough or hoarseness; dark urine; decreased urine output; diarrhea; difficult or labored breathing, irregular breathing, shortness of breath or rapid, shallow breathing; dilated neck veins; dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly; facial swelling; fainting; fast, pounding or irregular heartbeat or pulse; fever; headache; itching; loss of appetite; lower back or side pain; nausea; nervousness; painful cold sores or blisters on lips, nose, eyes or genitals; painful or difficult urination; pale skin; pinhead-sized red spots on skin; pounding in the ears; rash with flat lesions or small, raised lesions on the skin; slow or fast heartbeat; sore throat; sores, ulcers or white spots on lips or in mouth; stomach pain; sweating; swelling; swollen glands; tightness in chest; troubled breathing with exertion; unpleasant breath odor; unusual bleeding or bruising; unusual tiredness or weakness; vomiting; vomiting of blood; warmth on skin; weight gain; wheezing; yellow eyes or skin. 

For information on how to manage the costs of drug therapy, please see Financial Support, or to speak with an Information Specialist, call (800) 955-4572.