Indications and Usage

Chlorambucil is FDA approved to treat people who have chronic lymphocytic leukemia (CLL), some types of non-Hodgkin lymphoma and advanced Hodgkin lymphoma.

Side effects needing medical attention

Convulsions; cough; fever; chills; sore throat; flank or stomach pain; shortness of breath; rash; sores in the mouth and on the lips; swelling of feet or lower legs; unusual bleeding or bruising; yellowing of eyes and skin; black, tarry stools; blood in urine or stool; hoarseness; lower back or side pain; painful or difficult urination; pinhead-sized red spots on skin; agitation; blisters; hallucinations (seeing, hearing or feeling things that are not there); muscle twitching; peeling or scaling of skin; tremors; trouble walking; weakness (severe) or paralysis; changes in menstrual periods; itching of skin; nausea and vomiting.

Side effects needing medical attention after stopping this medication

Cough; fever; chills; sore throat; shortness of breath; unusual bleeding or bruising; black, tarry stools; blood in urine or stool; pinhead-sized red spots on skin; diarrhea; dizziness; faintness or lightheadedness when getting up from a lying or sitting position; headache; itching, hives or rash; nausea and vomiting; pale skin; painful or difficult urination; sores, ulcers or white spots on lips or in mouth, or painful cold sores or blisters on lips, nose, eyes or genitals; sudden sweating; swollen glands; tightness in chest; troubled breathing after exertion; unusual tiredness or weakness; wheezing; back pain; bone pain; burning, crawling, itching, numbness, prickling, "pins and needles" or tingling feelings; heartburn; lack or loss of strength;loss of appetite; muscle aches; sleeplessness; stomach discomfort, upset or pain, or acid or sour stomach; swelling or inflammation of the mouth; weight loss.

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