| Generic name | Busulfan |
| Pronunciation | byoo-SUL-fan |
| Brand name(s), other common name(s) | Busulfex®, Myleran® |
| Drug type | DNA-damaging agent |
| How the drug is given | By mouth or intravenously (IV) |
Indications and Usage
Busulfan is FDA approved in combination with cyclophosphamide as a conditioning regimen prior to allogeneic stem cell transplantation for people who have chronic myeloid leukemia.
Side effects needing medical attention
Fever, chills, or sore throat; unusual bleeding or bruising; cough; joint pain; shortness of breath; swelling of feet or lower legs; black, tarry stools; blood in urine or stool; pinhead-sized red spots on skin; lower back or side pain; painful or difficult urination; sores in mouth and on lips; darkening of the skin; confusion; diarrhea; dizziness; loss of appetite; nausea and vomiting; unusual tiredness; weakness; weight loss.
Side effects needing medical attention after stopping this medication
Fever; cough; shortness of breath; unusual bleeding or bruising; black, tarry stools; blood in urine or stool; chills; hoarseness; lower back or side pain; painful or difficult urination; pinhead-sized red spots on skin.
For information on how to manage the costs of drug therapy, please see Financial Support, or to speak with an Information Specialist, call (800) 955-4572.