The LLS Children’s Initiative Latest News

September 3, 2020, Rye Brook, N.Y. and Raleigh, N.C. - The Leukemia & Lymphoma Society (LLS) and PRA Health Sciences (NASDAQ: PRAH) announced today a partnership to launch a first-of-its-kind global master clinical trial to develop new treatments for children with relapsed acute leukemia. The new LLS PedAL (Pediatric Acute Leukemia) master clinical trial will test, simultaneously, multiple targeted therapies f...

June 17, 2020 (Rye Brook, NY)  -The Leukemia & Lymphoma Society (LLS) announced today a collaboration with the National Cancer Institute (NCI) and the Children’s Oncology Group (COG) to launch a global precision medicine clinical trial for children with acute leukemia. The three organizations share a commitment to address the urgent need for new, more precise and more effective treatments for children ...

  As we put the essential pieces together to launch a major precision medicine clinical trial for children with acute leukemia – LLS PedAL - one of the most important aspects of this trial will be its global reach. This LLS-led trial, which will test targeted therapies in children with acute myeloid leukemia, and eventually other high-risk leukemias, will benefit not only children in the United States, ...

Recently, Gwen Nichols, MD, Chief Medical Officer at LLS, shared her perspectives with STAT News on the urgent need to bring the promise of precision medicine to children with cancer. “Children with cancer are not benefiting enough from the progress we are making,” writes Dr. Nichols. Here at LLS, we’re calling for a full-scale renaissance in pediatric drug development and care to address this pressing challeng...

In the treatment of children with acute myeloid leukemia “We have plateaued. The tools in our toolbox are all sledgehammers.” This grim assessment was how Dr. E. Anders Kolb, of Nemours/Alfred I DuPont Hospital for Children, characterized the state of treatment for children with this devastating form of leukemia. Dr. Kolb was among a group of pediatric oncologists to join The Leukemia & Lymphoma Soc...

A key component of The LLS Children’s Initiative is supporting cutting edge research to accelerate the most impactful pediatric cancer science worldwide. LLS has committed to more than doubling our funding of research grants to find safer and more effective therapies for children, teens and young adults with blood cancers.  The areas of focus include:  Harnessing the immune system to kill canc...

As part of The LLS Children’s Initiative, LLS is working with a team of renowned pediatric oncologists to lay the groundwork for a global precision medicine master clinical trial to match children with relapsed acute leukemia to a targeted therapy based on the specific abnormalities driving their cancer. The goal of the LLS PedAL master clinical trial is to test multiple targeted therapies simultaneously at up t...